Objective: Cimetidine is a potent histamine H 2-receptor antagonist that is used for its ability to inhibit gastric acid secretion. This study investigated the effect of cimetidine on the ...

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Cimetidine 400mg or placebo was taken four times daily at approximately 8am, 1pm, 6pm and 11pm. All study medication was swallowed, without chewing, with 240ml of water. Participants fasted from ...