Objective: Cimetidine is a potent histamine H 2-receptor antagonist that is used for its ability to inhibit gastric acid secretion. This study investigated the effect of cimetidine on the ...

Participants were randomised to one of two treatment sequences, AB or BA, where: A: days 1 to 7 = - cimetidine 400mg four times daily; day 5 - gemifloxacin 320mg as a single dose; B: days 1 to 7 ...