环状RNA(circular RNA,circRNA)是一类不具有5'末端帽子和3'末端以共价键形成环状结构的RNA分子。随着高通量测序技术的发展以及生物信息学分析方法的进步,在多种细胞系和不同物种中陆续发现了大量的circRNA。与线性RNA表达相比,环状RNA的丰度相对较低 ...
一篇新的综述文章强调了环状RNA (circRNA)在癌症中的变革性作用,揭示了它作为肿瘤生物学中的关键角色和未来治疗的有希望的途径的潜力。曾经被认为是非编码RNA的circRNA,现在已经被证明可以编码功能性蛋白质,挑战传统的RNA生物学并开辟新的治疗可能性。
Circio and Entos have initiated a research collaboration that will involve joint development and in vivo delivery testing of ...
One of the startups, Levatio Therapeutics, is working on circular RNA medicines. Circular RNA is a closed RNA without 5′ or 3′ ends, a unique structure that prevents degradation by ...
A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.
A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.
A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both ...
Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...
Flagship Pioneering-backed Sail Biomedicines has laid off 12 employees following a review of the company’s organizational ...