However, it has a narrow therapeutic window, meaning that the difference between a therapeutic dose and a toxic dose is small. This characteristic makes colchicine poisoning a significant concern ...

An extensive literature review was performed to investigate the toxicity associated with i.v. and oral colchicine ... Gastrointestinal symptoms should not be used as an endpoint of therapy ...

Correspondence to: Mr P E Pritty, Accident and Emergency Department, Derbyshire Royal Infirmary, London Road, Derby DE1 2QY, UK; ppritty{at}aol.com Colchicine overdose is uncommon but potentially life ...

However, inadvertent drug interactions can result in unpredicted adverse outcomes. The toxicity of colchicine can manifest in various ways, ranging from mild and non-specific symptoms to severe form ...

This rule inaccurately predicted survival in a recent case. CASE REPORT: We present a case of fatal colchicine poisoning in an adult who ingested a maximum of 39.6 mg of colchicine (0.40 mg/kg).

The colchicine alkaloids in the lily can lead to life-threatening and fatal symptoms within hours of ingestion. Clinical signs range depending on the type of lily and its severity of toxicity.