Collagen, the body’s most abundant protein, has long been viewed as a predictable structural component of tissues. However, a ...
This turned out to be quite reasonable because it was known that polyproline formed a helix 3, of three residues per turn, which had the same backbone twist ... of a collagen fiber — with ...
In the new research, they found that cells migrated more than 50% faster on aligned collagen fibers than on random fibers. In addition, they found that cells use aligned fibers as directional cues ...
"The absence of the superhelical twist allows for molecular ... X-ray crystallography and fiber diffraction have provided valuable insights but could not capture collagen packing in complex ...