A cocrystal structure ... for this '21 st amino acid'. The structure resolves some mechanistic questions and allows for comparison of the tRNA-dependent synthesis of cysteine and selenocysteine.

Shining Loo of the XJTLU team Many bioactive proteins and peptides have multiple disulfide bonds between cysteine amino acids, which are crucial for maintaining their precise 3D folded structure.

Many bioactive proteins and peptides have multiple disulfide bonds between cysteine amino acids, which are crucial for maintaining their precise 3D folded structure. Drugs like linaclotide for ...