After informed consent and consultation between the midwife and attending obstetrician, the plan to administer 25 mcg of misoprostol (Cytotec) per vagina, every 4 hours, for up to 6 doses ...

The data suggest that absolute risks are low when misoprostol is used appropriately. We recommend 25 mcg vaginally every 4 to 6 hours for carefully selected patients in closely monitored settings.