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DMD was first described by French neurologist Guillaume Benjamin Amand Duchenne in the 1860s. However, until the 1980s, ...
Duchenne muscular dystrophy (DMD) is a rare neurological ... a sign of muscle cell damage. A muscle biopsy (tissue sample) is usually taken from the thigh muscle. Biopsy imaging examines muscle ...
DMD treatment KER-065 showed a good safety profile in a Phase 1 clinical trial with no serious side effects seen in healthy ...
Early screening for Duchenne muscular dystrophy can help you get early treatments and referrals for your child to help prevent further loss of muscle tissue. Duchenne muscular dystrophy (DMD ...
WVE-N531 showed significant improvements in functional measures and muscle health in DMD patients during the ... and the data demonstrated a 61-day tissue half-life that supports a once-monthly ...
Due to a genetic mutation in the DMD gene, people with Duchenne do not make functional dystrophin; their muscle cells are more sensitive to injury and muscle tissue is progressively replaced with scar ...
Keros plans on engaging with regulatory authorities, starting in the third quarter of 2025. Subject to the outcome of these regulatory interactions, Keros expects to initiate a Phase 2 clinical trial ...
Due to a genetic mutation in the DMD gene, people with Duchenne do not make functional dystrophin; their muscle cells are more sensitive to injury and muscle tissue is progressively replaced with ...
Two-year data showed significant functional improvements in patients treated with delandistrogene moxeparvovec compared to controls, despite initial trial endpoint failure. The treated group ...
In DMD, muscle fibres are highly susceptible to injury ... impairment of muscle regeneration and muscle replacement by fibrotic and fat tissue. 4, 5-7 The disease primarily affects boys, with ...