The discovery of restriction enzymes began with a hypothesis. In the 1960s, Werner Arber observed a dramatic change in the bacteriophage DNA after it invaded these resistant strains of bacteria ...

Restriction enzymes are one of the most important tools in the recombinant DNA technology toolbox. But how were these enzymes discovered? And what makes them so useful? Aa Aa Aa When I come to the ...

1 This discovery left a number of demethylating enzymes still at large, including those that demethylate lysine 9 and 36, and the enzymes that act upon trimethylated residues. Yi Zhang at the ...