Thus, viral ATP-dependent DNA ligases have an intrinsic nick-sensing function. Nick recognition by vaccinia DNA ligase and Chlorella virus DNA ligase also depends on occupancy of the AMP binding ...

"In simple type II R-M systems, methylase and restrictase are two separate proteins, whereas in BREX, both the methylation of its own DNA and the recognition and restriction of unmethylated viral ...

Scientists used the restriction enzymes to, among other things, cut DNA at particular locations and insert new genes at the cutting sites. However, it is difficult to determine in advance exactly ...

This article was originally published with the title “ The Recognition of DNA in Bacteria ” in Scientific American Magazine Vol. 222 No. 1 (January 1970), p. 88 doi:10.1038 ...

where this region is referred to as the recognition loop. The C-terminal tail. The third segment of Ig-fold transcription factors to interact with DNA is a C-terminal tail that extends from strand ...

More information: Alena Drobiazko et al, Molecular basis of foreign DNA recognition by BREX anti-phage immunity system, Nature Communications (2025). DOI: 10.1038/s41467-025-57006-2 Provided by ...

Our group retains an interest in the areas of structure-function studies of RNA interference mediated by siRNA pathway, and on post-translation histone and DNA modifications impacting on epigenetic ...

While these enzymes allow large DNA insertions, they only recognize specific recombinase recognition sites. “These recombinase recognition sites rarely occur in nature where we want to insert ...