DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers ...

Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, ...

A woman's egg cells are already formed in her body before she is born. However, with increasing age, DNA damage accumulates ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, constantly finding and reversing damage to our genetic code. Researchers ...

Consistent with the specific control of HR in rDNA, the dynamics of repair-protein foci are altered in the nucleolus 34. DNA damage caused to the rDNA by exogenous agents such as IR do not result ...

Therein lies an opportunity to stop it, according to scientists led by Sarah Tabrizi of University College London. In the February 12 Science Translational Medicine, they reported that taking down ...

Poly adenosine diphosphate-ribose polymerase (PARP) inhibitors, a class of targeted anticancer therapies, prevent genetic ...

These studies have consistently highlighted the role of DNA repair in influencing the age of onset and disease progression. Among the DNA repair genes identified, MSH3 has emerged as a ...

Boosting cells with a tardigrade protein reduced DNA damage after radiation, offering potential protection for healthy tissue ...