DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers ...

Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But ...

Aging significantly impacts neurodegeneration, increasing risks for diseases like Alzheimer's. Research focuses on therapies ...

In the February 12 Science Translational Medicine, they reported that taking down MSH3, a DNA repair protein, nipped CAG expansion in the bud. The DNA repair protein MSH3 promotes the growth of CAG ...

Scientists discovered a way to block hepatitis B infection using an anticancer drug, offering hope for new treatments.

Poly adenosine diphosphate-ribose polymerase (PARP) inhibitors, a class of targeted anticancer therapies, prevent genetic ...

This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, constantly finding and reversing damage to our genetic code. Researchers ...

More information: Ninadini Sharma et al, Changes in DNA repair compartments and cohesin loss promote DNA damage accumulation in aged oocytes, Current Biology (2024). DOI: 10.1016/j.cub.2024.09.040 ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...