Gene regulation underpins nearly every biological process—from cell development to responses to environmental changes, and understanding it can provide insights into cancer and other diseases. Now, ...

In the 1960s, Werner Arber observed a dramatic change in the bacteriophage DNA after it invaded these resistant strains of bacteria: It was degraded and cut into pieces. In an attempt to explain ...

These strains shared a sequence identity of 99%. Although the basic biology and genetics of influenza viruses are fairly well understood, heading off future pandemics requires a better ...

These strains had genetic changes in genes that control the fungus's system which repairs mutated DNA—known as the mismatch repair system. By using CRISPR-Cas9 to reproduce these variants in the ...

A new study from the University of Toronto has found that a low-carbohydrate diet may increase the risk of colorectal cancer ...

Positive-culture patients were classified on the basis of genetic (DNA strain) and epidemiological (close contact with a positive-TB patient prior to diagnosis) variables. Three groups were identified ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...