Each of us has enough DNA to reach from here to the sun and back, more than 300 times. How is all of that DNA packaged so tightly into chromosomes and squeezed into a tiny nucleus? Histones are a ...

Histones are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin. Nuclear DNA does not appear in free linear strands; it is highly condensed and ...

The mechanism of a peculiar type of heterochromatin, used by embryonic stem cells to silence 'parasitic' DNA-elements within the context of their highly dynamic pluripotent chromatin. Disclaimer ...

In most cells, DNA is wrapped around proteins called histones, allowing it to be loosely packed and accessible for gene activity ... stepwise transformation of DNA structures as they bind to ...