TAGCyx is building a pipeline of Xenoligo aptamers and aptamer–drug conjugates ... compared to conventional DNA and RNA aptamers, including improved binding capability, specificity and stability.” ...

Certain DNA sequences are bound ... surprising because small molecule binding sites on transcription factors are quite uncommon. A common analogy is that drugs bind to proteins like keys inside ...

The DEC-Tec library of drug-like molecules, each of which is attached to a unique DNA sequence that acts as a “bar code” defining its synthesis, can be incubated in a single tube with a target protein ...

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously “undruggable ... fires across to the target and won’t let go – it grips the cJun ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana ...

Named Deep Predictor of Binding Specificity ... development of new drugs and medical treatments by providing more efficient predictions of how proteins interact with DNA. DeepPBS is built on ...

University of Arkansas for Medical Sciences (UAMS) researcher Kevin Raney, Ph.D., has been awarded a five-year, $2.99 million ...