The completion of mitosis is governed by the dephosphorylation of cyclin-dependent kinase (Cdk) substrates and by the ubiquitination of anaphase-promoting complex (APC) substrates. The order in ...

But the protein kinases that suppress sleep and the dephosphorylation enzymes that control sleep and wakefulness have not been fully elucidated. Animals, including humans, require a certain amount ...