Purpose: Smith-Magenis syndrome (SMS) is a complex disorder that includes mental retardation, craniofacial and skeletal ... SMS300 showed a heterozygous deletion of four bases, GCCG, starting ...

1p36 Deletion Syndrome (1p36DS) is a genetic condition ... including distinct craniofacial features, developmental delays, hypotonia (reduced muscle tone), epilepsy, and various heart defects.