The high-resolution structure of an oxidoreductase ... eukaryotic ER lumen which facilitates native disulfide bond formation in nascent secretory proteins by rearranging incorrect disulfides.

One common protein-engineering goal is increasing the thermostability of an enzyme. Structure-based approaches ... stabilizing interactions such as disulfide bonds or salt bridges, stabilize ...

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Protein antigens typically ... of five identical subunits connected by disulfide bonds and a J chain. This pentameric form is the predominant structure of IgM. In addition to the pentameric ...