But, perhaps a more underrated pick for Spider-Man's greatest foe is the wonderfully complex Doctor Otto Octavius, aka Doctor Octopus. Peter Parker's personal life is constantly full of strife.

aka Otto Octavius, to the mix. Voiced by Hugh Dancy, the evil genius is revealed to be the mastermind who supplied futuristic inventions to criminals across New York City. However, Doctor Octopus ...

As rumours swirl about Spider-Man 4's mysterious female villain, we're counting down six sinister possibilities, all of whom ...