A new pill, tavapadon, has shown potential in easing Parkinson’s symptoms while limiting side effects. In patients taking at ...

because they do not cause behavioral signs associated with activation of either normosensitive or supersensitive postsynaptic dopamine D 2 receptors (e.g., increased locomotion in reserpinized ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

Levodopa — which is converted into dopamine in the brain and targets the D2/D3/D4 dopamine receptors — has been linked to side effects including sleep disorders, hallucinations, impulse ...

"Instead, we found the types of dopamine receptors on the brain cells, and the ratio in which they are found, better predicted cognitive performance." Study participants who had a higher ratio of ...

Nearly 16 million American adults have been diagnosed with attention deficit hyperactivity disorder (ADHD), but evidence suggests that more than 30 ...

The highly selective partial agonist at D1 and D5 receptors significantly improves motor function in patients recently ...

Fixed and flexible doses of tavapadon significantly improved motor function compared with placebo in patients with ...