A reduction in renal perfusion normally results in dilatation of the glomerular afferent arteriole and constriction of the glomerular efferent arteriole so that glomerular capillary hydrostatic ...

Reproduced with permission from [1]. Endothelin-1 Causes vasoconstriction of both afferent and efferent arterioles, leading to decreased renal blood flow and glomerular filtration rate [127,128] ...