Morphology-controlling genes frequently react to multiple separate enhancers, each of which controls the gene's expression in a distinct body part. Enhancers were formerly believed to be modular.

before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or off. Understanding enhancer function is very important, since they ...

Different enhancers are therefore separated from each other, even if they control the same gene, and switch it on in different parts of the body. A recent study from the University of Bonn and the ...

Enhancer Biology lab studies gene regulation and genome architecture controlled by transcription factors using genome-wide functional genomics methods. Our aim is to understand enhancer malfunction ...

New study by Chiba University, Japan in collaboration with Karolinska Institutet, Sweden, uncovers novel enhancer-promoter interactions that regulate gene expression during neuronal ...

This shows that the region contains several non-modular enhancers (blue = strong gene expression; red = weak gene expression). The image may be used in combination with the press release.