Researchers discovered that ALPK2, a heart-specific enzyme, may protect against HFpEF by activating TPM1 in heart muscle ...

Researchers from the Nagoya University Graduate School of Medicine identified an enzyme, alpha-kinase 2 (ALPK2) that is ...

Phosphorylation can either activate a protein (orange) or inactivate it (green). Kinase is an enzyme that phosphorylates proteins. Phosphatase is an enzyme that dephosphorylates proteins ...

What is ALPK2, and how can it help treat heart failure? Researchers have found that this heart-specific enzyme may prevent ...

Enzymes lower the activation energy necessary ... the citric acid cycle, and oxidative phosphorylation. Protein surfaces are designed for interaction. Learn how proteins can bind and release ...

Enzymes can be regulated by various means, such as allosteric regulation (binding of effector molecules), covalent modification (e.g., phosphorylation), and changes in pH or temperature. The Michaelis ...

The process of protein phosphorylation is central to regulating various functions in the body, including how well the heart pumps blood out. The process is controlled by enzymes called protein ...