After some high-profile crashes, the one-time biotech darling is inching toward success with its Hunter syndrome treatment, ...

Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson's disease, and other serious illnesses. Now, a new ...

BioMarin's Phase 3 trial shows Palynziq significantly reduces blood Phe in adolescents with PKU. The company plans a ...

Enzymes, the core catalysts in life, drive critical biological processes ranging from metabolic regulation to energy ...

New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation. For organs to develop, grow and regenerate, cells must proliferate.

Only one type of enzyme supplement—called pancreatic enzyme replacement therapy (PERT)—is available. PERT is a Food and Drug Administration (FDA)–regulated prescription medication.

Objective: To compare the short-term efficacy and tolerability of an oral enzyme therapy with the NSAID diclofenac in patients with symptomatic osteoarthritis of the knee (gonarthritis).

BioMarin Pharmaceutical has reported that the multi-centre Phase III PEGASUS trial of Palynziq (pegvaliase-pqpz) has met its ...

People with inflammatory bowel disease (IBD) also have an increased risk of developing colorectal cancer. However, the exact ...