Heimberger said. Finally, to translate their findings to preclinical models, the investigators used epigenetic editing and lineage tracing approaches in human meningioma co-culture models to ...

Gene expression is regulated by transcription factors in concert with epigenetic modifications (such as DNA methylation, post-translational histone modifications, the position and compaction of ...

Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.