Epigenetic regulation mediates adaptation to ... Recent use of a genetically manipulated mouse model of Rett's syndrome demonstrated that imposing normal levels of MeCP2 in neurons reversed ...

Accumulating evidence indicates that epigenetic modifiers have key roles in genome-wide reprogramming and activation and repression of specific genes during mammalian germ-cell development.

To do so, they developed a transgenic mouse model carrying a slime mold endonuclease that, when treated with the drug tamoxifen, induces in the animal’s genome, triggering DNA repair and the resulting ...

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

This, in the past decade, has led to the development of epigenetic clocks, new computational tools that can estimate an organism's age by analyzing the accumulation of epigenetic marks in cells ...

Historically, therapies for ASD and ID have primarily targeted managing symptoms, such as behavioral issues or communication ...

Can autism symptoms be reversed after brain development? A new JNCASR study suggests it might be possible with a sugar-linked ...

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