The activation/deactivation of genes is controlled by so-called epigenetic modifications, i.e., chemical groups attached to ...

Epigenetic changes can switch genes on or off and determine which proteins are transcribed. Epigenetics is involved in many normal cellular processes. Consider the fact that our cells all have the ...

Chromatin loops form a simple epigenetic switch that regulates Igf2 expression, according to the authors of a letter in Nature Genetics this week. The mechanism could model epigenetic regulation of ...

This "epigenetic" switch is the lynchpin to understanding how renin production is controlled in these cells that don't normally produce renin. "We expected to find the region in your genome where ...

The behavior of a person's genes doesn't just depend on the genes' DNA sequence - it's also affected by so-called epigenetic factors. Changes in these factors can play a critical role in disease.

By identifying and activating a master epigenetic switch using CRISPR, the researchers showed they can turn on many naturally suppressed genes from one parent to compensate for defects in the same ...

By identifying and activating a master epigenetic switch using CRISPR, the researchers showed they can turn on many naturally suppressed genes from one parent to compensate for defects in the same ...

A high throughput screen of >30,000 diverse repressor domains from across the tree of life identifies repressor domains with unique structures that underpin enhanced epigenetic effector domain ...