A new study indicates that it may also function early in tumour ... the EMT program permits cells that were previously integral components of epithelial cell sheets to break their associations ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

These models include humanized stem cell-derived in vitro systems that recreate the epithelial cell layer makeup and morphology. 2 Towards this end, scientists increasingly employ monolayer systems.

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

Colorectal cancer (CRC) is a major health problem, with an alarming increase of early-onset CRC (EO-CRC) cases among ...

UC San Diego researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease ...