The main goal of the Fuqua Lab's research is to determine the role of specific somatic mutations in estrogen receptor alpha, called K303R and Y537N ERa, in the clinical problem of hormone resistance.

Many of these functions are mediated by estrogen binding to one of its receptors, ER-alpha," said co-corresponding author Dr.

Collins and Webb reply—In no way did we intend to give the impression that estrogen receptors on the surface of plasma membranes or intracellular coupling was a new concept. Our News & Views ...

BCs can be further classified into three subtypes, based on their molecular identifications: Estrogen Receptor alpha (ERα)-positive, Her2 (human epidermal growth factor receptor 2)-positive, and ...

Estrogen Receptor Alpha,Expression In Vascular Cells,Fetal Bovine Serum,Fluorescein Isothiocyanate,Food And Drug Administration,Functional Assays,Gene Glyceraldehyde-3-phosphate Dehydrogenase,High ...

More than 60 years after its discovery, the estrogen receptor (ER) remains the most important biomarker in breast oncology. ER status is essential in clinical decisions and predicting outcomes for ...

Experimental results showed that adipocyte ESRRA interferes with the signaling of 17-estradiol and estrogen receptor alpha, resulting in the transcriptional repression of secreted phosphoprotein 1 ...