We have investigated the role of mitochondrial calcium buffering in excitotoxic cell death. Glutamate acts at NMDA receptors in cultured rat forebrain neurons to increase the intracellular free ...

Background and aims: We have recently shown that Dextromethorphan is neuroprotective against excitotoxic and hyperoxic-induced brain injury. Beside its antagonistic effect on the NMDA [N-methyl-D ...