In hepatocytes, ferroptosis faces physiological constraints due to the liver's multilayered antioxidant systems. These include ferritin-mediated iron sequestration, GPx4 activity, and high levels ...
Contrary to hepcidin, ferritin levels were more strongly boosted by pathogen-induced inflammation ... Hepcidin is a major iron-regulating peptide hormone that is produced in the liver. Through the ...
SF >1000 µg/l is associated with a substantial risk of cirrhosis and therefore a liver biopsy is recommended for staging. C282Y homozygous patients with normal or mildly elevated ferritin can ...
Ferritin is an iron storage protein present in all cells that can be measured in serum, plasma, liver, red blood cells, and other specimens. Serum or plasma ferritin is easily measured and widely used ...