Interestingly, it has been observed that chimeric fusion genes sometimes involve two copies of the same gene (e.g., the alcohol dehydrogenase gene in Drosophila), and when that happens ...

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

A new study has revealed the existence of bifunctional diterpene cyclases/synthases (DCSs) in bacteria, offering compelling evidence that the plant terpene synthase gene family, termed TPS, originated ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 ...

Whole genome sequencing can be an exceptionally valuable tool in cancer diagnostics. The application of this technique can ...

We have investigated the prediction of protein interactions through the analysis of domain fusion to assess whether metabolic enzymes have a higher participation in gene-fusion events compared ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 ...

gene fusion who have disease progression on or after prior systemic therapy. “This manuscript provides comprehensive data on the safety and efficacy of Bizengri and demonstrates the meaningful ...

UTRECHT, The Netherlands and CAMBRIDGE, Mass., Feb. 05, 2025 (GLOBE NEWSWIRE) -- Merus N.V. (Nasdaq: MRUS) (Merus, the Company, we, or our), a ...