Laser Biomedical Research Center, G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, United States ...

A new vector has been developed that integrates the Cre enzyme gene with its target DNA sequence, loxP, enabling the creation of Cre-loxP organisms in a single step.

A recent study led by the Universitat Autònoma de Barcelona (UAB) demonstrates the potential of gene therapy to restore motor ...

A recent study demonstrated the potential of gene therapy to restore motor capacity in an ultra-rare disease, megalencephalic ...

the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short DNA sequence called TAx9 before the promoter region of the Cre gene, thereby preventing its expression in ...

A recent study led by the UAB demonstrates the potential of gene therapy to restore motor capacity in an ultra-rare disease, ...

That is concentrating on determining where the vector integrated into the chromosomes of the two patients with cancer, and if that has resulted in changes to gene expression in neighbouring areas.

optimizing ARSA gene expression and enhancing safety. They also used the smallest amount of viral vector possible in both preclinical and human hematopoietic stem cells. This is important because ...