A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States Food and Drug ...

引言脑肿瘤治疗领域正面临一个令人困惑的谜题：为何在其他癌症中屡建奇功的免疫治疗，对恶性胶质瘤却频频失效？2月26日发表于《Nature》的研究“Programs, origins and immunomodulatory functions of ...

2017年7月5日，南京医科大学附属淮安第一人民医院神经外科在Oncology Research（中科院四区 IF=2）期刊上在线发表题为 "Overexpression of Protease Serine 8 Inhibits Glioma ...

Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting ...

Scientists at UCLA have discovered a potential new way to treat glioblastoma, the most aggressive type of brain cancer. Their ...

随后科学家们将非免疫抑制性的骨髓细胞暴露于地塞米松疗法中，结果发现其很快就变得具有免疫抑制性了，这种效应具有较长的持久性且在最后一次给药后仍能维持数周的作用效果。在一些癌症患者中，临床医生会给其使用一些疗法来增强其机体抵御恶性细胞的免疫反应，从而来帮 ...

Malignant gliomas and medulloblastomas also exhibit heterogeneity at the cellular level, with subpopulations of tumour cells harbouring stem-like properties rendering them more resistant to therapy.

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than ...

High-grade glioma, an aggressive form of pediatric and adult brain cancer, is challenging to treat given the tumor location, incidence of recurrence ...

New research by Yale has found an association between exposure to chemicals commonly used in firefighting and incidence of a brain tumor called a glioma in firefights, suggesting that the cancer may ...

Brain tumours remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular ...

At the heart of the deal is the drug candidate dordaviprone, which is months away from a regulatory verdict for its use in H3 ...