"This causes a metabolic phenotype that resembles a glutamine synthetase deficiency, which can be characterized by increased glutamate and ammonia levels and decreased glutamine levels." ...

Medically reviewed by Beth Thomas, PharmD Glutamine is the most common amino acid (a building block of protein) in the blood.

This established that the glutamine active site is chemically distinct and produces ammonia, which is transferred through the tunnel to the second active site. Based on ideas from the closed-loop ...