Glutamine synthetase (GS) is an ancient enzyme present in all domains of life ... of the CDC20-mediated anaphase-promoting complex/cyclosome (APC/C), ensuring proper mitotic progression. The study ...

Results: Exposure to basolateral TNF-α (20 ng/ml) for six hours induced translocation of E coli across Caco-2 but only if accompanied by simultaneous glutamine depletion (p<0.01). Translocation was ...

1 Plasma glutamine levels may decrease by 58% during critical illness and remain depleted for up to three weeks.1 Glutamine depletion has been associated with increased risk of infectious ...

"This causes a metabolic phenotype that resembles a glutamine synthetase deficiency, which can be characterized by increased glutamate and ammonia levels and decreased glutamine levels." ...

A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Koya Kawase, a pediatric doctor at Nagoya City University ...