The pneumococcal enzyme SpGH101 cleaves core-1 O-linked ... using a two-step process involving EndoA or EndoM. Peptide-N-glycosidase F-deglycosylated monoclonal antibodies can be transported ...

In addition, we are also modifying glycosidase enzymes (in collaboration with Dr. T.J. Borgford) with the aim of enabling the mutant enzymes to transfer unnatural glycosyl analogues onto biologically ...