Thirdly, we review experience treating children either with recombinant human (rh) insulin-like growth factor (IGF ... hormone) result in disturbance of the growth-hormone–IGF1 axis. Box 1 ...

both hypothalamic hormones 1. Growth hormone increases production of insulin-like growth factor-I (IGF-I) primarily in the liver, as well as other target organs. Both IGF-I and GH provide feedback ...

Researchers studying over 2,000 Ashkenazi Jewish centenarians uncovered two rare IGF-1 gene variants linked to exceptional longevity. These variants reduce IGF-1 receptor activity through either ...

In recent years, there has been a great interest in anabolic hormone replacement therapy – namely, growth hormone and ... the efficacy and safety of GH/IGF-1 and testosterone supplementation ...