The involvement of noncoding mRNAs in many regulatory processes, their abundance, and their diversity of functions has led to the hypothesis that an "RNA world" may have preceded the evolution of ...

In addition cyclophilins play roles in inflammation and cancer and are already the target of several clinical drugs such as cyclosporin A. Surprisingly, this family has been robustly identified as ...

. Published by Cold Spring Harbor Laboratory Press, 10 Skyline Drive, Plainview, New York, USA; 1998, 726 pages. $145.00. It is well established that RNA structure is essential for the function of ...

Users learn that molecular shape determines RNA function and allows RNA strands to carry out a wide variety of jobs essential for life. The Lab also features a series of animated videos that ...

Our investigations of exosomes in budding yeast revealed that its central channel is essential, and that it functions to guide RNA substrates to the active sites of both Dis3 and Rrp6. We subsequently ...

That’s a big problem, because the precise shape that an RNA molecule folds into determines its function ... at predicting the patterns that guide RNA folding, as described in a recent paper ...

it has been challenging to determine whether specific RNA molecules are essential for cell function. “We now have this ...

Despite the significant advances in understanding the roles of inosine in RNA biology, several challenges remain. One of the main challenges is elucidating the precise mechanisms by which A-to-I ...

RNA is integral to cellular function because it encodes regulatory elements that influence gene expression, translation, and structural organization. In plants, secondary and tertiary RNA ...