Initial screening assays were performed with a large number of typical and atypical antipsychotic drugs. In preliminary studies, we discovered that selected typical and atypical antipsychotic ...

This observation led Swedish investigators to propose, in 1948, that there are two types of receptors sensitive to histamine, and close to two decades later British researchers gave the name H1 to ...

This study revealed an association between elevated hepatic histamine levels and erythropoietic protoporphyria progression.

In the following section, the various methods used to evaluate antihistamines illustrate the developmental process for evaluating the efficacy of the H 1-receptor antagonist desloratadine.

In vitro tests have demonstrated that second-generation antihistamines have improved H 1-receptor specificity and a slower dissociation rate compared with first-generation antihistamines ...

It is classified as a first-generation H1 antihistamine and is primarily used for the treatment of allergies as well as motion sickness and nausea. First-generation H1 antihistamines like Benadryl ...

Despite concerns on the major neuropsychiatric side effects for long-term use of H1-receptor antagonist (anti-histamine, AH), one of the major therapeutic tools for allergic diseases, their ...

However, even if you don't know what caused your child to break out in hives, the symptoms can be safely and effectively ...