Assays for hepatitis B surface antigen (HBsAg) are the most frequently used tests to detect HBV infection. Vaccination for HBV can produce transiently detectable levels of HBsAg in patients.

The following is a summary of "Impact of HBsAg reduction via siRNA treatment on natural and vaccine (BRII-179)-induced ...

Furthermore, the reduced levels persisted below 100 IU/mL for up to one year, with four subjects experiencing complete HBsAg loss within 21 days post-infusion. SCG101’s safety profile was ...

with the goal to maximize cumulative viral editing to achieve undetectable levels of HBsAg. With a well-tolerated safety profile and early antiviral activity established at pre-specified ...

Two of three participants showed a substantial reduction in HBsAg after the first dose ... With a well-tolerated safety profile and early antiviral activity established at pre-specified time ...