although there is incomplete biochemical and clinical penetrance and variable phenotypic expression of the HFE mutation in hereditary hemochromatosis. An elevated SF <1000 µg/l is associated with ...

Type 1 hereditary hemochromatosis is a common disorder of iron overload occurring in individuals homozygous for the C282Y HFE gene mutation. It can be a progressive and fatal condition.

A condition that causes excess iron accumulation in the body Medically reviewed by Benjamin Leach, MD Hemochromatosis is a ...

BMP, bone morphogenetic protein; BMPR, bone morphogenetic protein receptor; HAMP, hepcidin; HFE, hereditary hemochromatosis protein; HJV, hemojuvelin; Holo-Tf, holo ...

This hereditary condition has sometimes been called a "silent killer," according to the Canadian Hemochromatosis Society. While it's a condition that's genetic, the disorder still remains relatively ...