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这篇研究发现,潜伏感染小鼠的鼻相关淋巴组织(NALT)中存在人类 α 疱疹病毒 1(HSV-1)DNA,地塞米松(DEX)能诱导其复制。研究还确定了携带病毒 DNA 的细胞类型,为 HSV-1 相关疾病研究提供新视角,值得关注。
Genital herpes simplex virus (HSV) infections are frequently asymptomatic or undiagnosed, but more than half the US population is seropositive for HSV, and about one-fifth are positive for HSV-2.
Antibodies peak 12-21 days after initial infection, which permits serologic testing that can use monoclonal antibodies to a glycoprotein in the HSV envelope or by using a modified Western blot ...