Monoclonal antibodies (mAbs) are nature's biological ... are treated with other immunosuppressants and are less prone to HAMA reactions. If mAbs were to become a class of successful therapeutics ...

While mouse monoclonal antibodies are specific, they are extremely immunogenic and can potentially induce human anti-mouse antibody (HAMA) responses, effectively compromising therapeutic ...

the clinical application of mouse monoclonal antibodies is limited by the human anti-mouse antibody (HAMA) response. Humanization of mouse monoclonal antibodies or alpaca nanobody by genetic ...