本研究针对多发性骨髓瘤(MM)患者对一线药物来那度胺(LEN)的获得性耐药机制展开探索。南京第二医院团队发现转录因子YY1通过结合AKR1C3启动子区激活其表达，进而激活Hedgehog信号通路，促进糖酵解代谢重编程，最终导致LEN耐药。该研究揭示了YY1-AKR1C3-Hedgehog轴在MM ...

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Do You Hate Having to Mow the Lawn on the Weekends? Most likely. Given that AI can mow your lawn more intelligently, ...

The release, known as Android Studio Hedgehog, is designed to boost developer productivity, according to the company in a blog post. The App Quality Insights feature now incorporates Android ...

Utilizing AI-generated visuals ... work of imaginative creativity rather than a legitimate production. Sonic the Hedgehog 4 is set for a Spring 2027 with its expected release date into theaters ...