The injury-repair process of the airway epithelium may contribute to the development of the bronchial hyper-responsiveness that is documented in many elite athletes. There are several reasons why the ...

Culture-independent studies of asthmatic bronchoscopic samples have demonstrated relationships between airway microbiota composition and the severity of bronchial hyper-responsiveness. Chronic ...

Smokers' airways are hyper-reactive, meaning they sometimes can be hyper-responsive to non-noxious stimuli also, and smoking cessation is found to prevent further progression of airway hyper ...

Winter athletes have a high prevalence of respiratory symptoms and airway hyper-responsiveness to methacholine and hyperpnoea. The acute effects of exercise in cold air are neutrophil influx as ...

The goal of this proposal is to investigate the novel concept that oxidant-modified self-peptides produced by regulatory airway immune cells can trigger airway hyper-responsiveness(AHR). We have ...