Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

The following is a summary of “Biomarkers of oxidation, inflammation and intestinal permeability in persons with diabetes mellitus with parenteral nutrition: A multicenter randomized trial,” published ...

Tumor necrosis factor (TNF)-alpha, a proinflammatory cytokine ... in which 15 patients with mild-to-severe AD were treated for 6 months. We administered etanercept, 25-50 mg, once weekly by ...

Isomyosamine targets excess pro-inflammatory TNF-alpha, a primary cause of sarcopenia. "Findings from the initial observational study will inform our forward move into multiple planned clinical ...

3 TNF inhibitor drug category: the global market value for TNF inhibitors was estimated to be $39.7 billion in 2024. Growing at an expected CAGR of 3.6% for the ... TNF-alpha (TNF-α), an immune ...