研究结果表明,TGF-β信号阻断是NK细胞有效对抗肝细胞和其他表达高水平TGF-β的恶性肿瘤的必要条件。 这项研究证明了使用 ipsc 来源细胞替代大泡性 ...
帕金森病(Parkinson’s Disease,PD),是一种复杂的神经退行性疾病,也是世界上第二常见的神经退行性疾病,仅次于阿尔茨海默病(AD),影响着约 1?% 的 65 岁及以上老人。随着全球人口老龄化,帕金森病患病率还将大幅增加。 人诱导多能干细胞(hiPSC)来源的中脑多巴胺能细胞(mDAC)为帕金森病的自体细胞疗法提供了一个有前景的来源,但标准化的调控标准对于临床转化至关重要。 20 ...
CD16 iPSC-derived NK (iNK) cell – Fate’s lead iPSC-derived cancer immunotherapy is a targeted iNK cell product created from a master engineered pluripotent cell line that expresses a high ...
诱导多能干细胞(iPSC)能再分化成特定的细胞类型、组织和器官,联合基因编辑技术使用,可用于探索疾病发生的机制、开发新型有效的药物和细胞 ...
Barclays 27 th Annual Global Healthcare Conference, including a fireside chat at 8:30 AM ET on Tuesday, March 11, 2025 in ...
We have dedicated cleanrooms for induced pluripotent stem cells (iPSC), mesenchymal stromal cells (MSC), chimeric antigen receptor T-cells (CAR-T), T-cell receptor-engineered T-cells (TCR-T), natural ...
The trial, dubbed CARAMEL, will mark the first evaluation of an allogeneic iPSC-derived CD19-directed NK cell therapy in autoimmune disorders. The investigator-initiated trial, sponsored by ...
Chen became a graduate student for the Spencer lab in May of 2015. After graduating in , Chen became a post doc for the Spencer Lab. Following the completion of her post-doctoral work, Chen took a ...