most probably as a consequence of dynamic exchange between the two different IgG4 antibody half-molecules. Titration studies indicated that the exchange shows no preference for the original or a ...

Note that IgG4 antibodies are bispecific due to exchange of half molecules after synthesis. This renders them 'invisible' in bridging-type ELISA. ADA: Antidrug antibody; E: Enzyme; Fc: Fragment ...

WASHINGTON -- Patients with IgG4-related disease appeared to benefit ... Mean age was 58 and about two-thirds were men. Just under half were newly diagnosed; the rest had recurrent illness lasting ...