Most clinically relevant T-cell receptor (TCR)-engineered T cells are typically tested in immunocompromised mice, allowing human T-cell engraftment but failing to replicate the complex interactions of ...

(3, 5) Scientists took human pancreatic cancer cells and transplanted them into immunocompromised mice. The mice then received an injection of PJ34 for 14-days straight. One month later ...

It parallels earlier work done at the center to better understand how the immune systems of people who are immunocompromised respond to vaccines against SARS-CoV-2, the virus that causes COVID-19.

even for mice that were immunocompromised. “Modified BCG elicited similar immune responses and provided similar protection against Mtb challenge as wild-type BCG in mice,” the investigators wrote.

It parallels earlier work done at the center to better understand how the immune systems of people who are immunocompromised respond to vaccines against SARS-CoV-2, the virus that causes COVID-19.

particularly in immunocompromised patients, with mortality rates of up to 25%. While studying yeast infections in laboratory mice, Steffen Jung and colleagues at the Weizmann Institute discovered ...

Noroviruses are increasingly recognized as an important cause of chronic gastroenteritis in immunocompromised patients, as reflected by the growing number of clinical case reports. This review ...

Yearly administration of the influenza vaccine is the main strategy to prevent influenza in immunocompromised patients. Here, we reviewed the recent literature regarding the clinical significance ...

Relevant preclinical models are vital to ensuring that time and money are invested in advancing the most effective drug candidates. While traditional cell line-derived xenograft (CDX) models generated ...